Week 4 of the 2024 college football season brings plenty of action with three games featuring the top 25 teams competing on the weekend. The two games feature opponents ranked in the top-15 of the latest AP Top 25 poll, and several programs are set to make their official meetings when league play begins.
That includes No. 11 USC, entering its first Big Ten game with a trip to No. 18 Michigan in the network seat. The Wolverines have already lost one top-25 game at home this season, so there is plenty of motivation to knock off the favored Trojans and keep their College Football Playoff hopes alive. .
No. 12 Utah enters its third conference of the century as it visits No. 14 Oklahoma State for the Big 12 showdown. All eyes are on the status of Utes quarterback Cameron Rising, who missed his team’s Week 3 win with an injured finger on his throwing hand. Coach Kyle Whittingham said the plan is for Rising to return, but it remains a situation to be evaluated.
Now, No. 15 Oklahoma hosts No. 6 Tennessee in a game full of stories. Josh Heupel returns to Norman as Tennessee’s coach, while Oklahoma plays its first SEC game. The winner takes an important step toward the College Football Playoff.
Be sure to stay with CBS Sports all day Saturday for college football coverage from start to finish. Let’s take a look at our expert picks for the best games in Week 4.
Odds by SportsLine consensus | Always in the East
Marshall at No. 3 Ohio State
Day | Fox, chest (Try it for free) — Can Marshall do something amazing? Of course, everything is possible, but there is a chance that this will be another wasted issue. The Buckeyes haven’t allowed a hit this season, and while they’ve taken their starters early, it hasn’t stopped them from scoring in either of their first two games. The Buckeyes put themselves on a three-game winning streak with this non-conference schedule, and it’s possible they’ll find themselves in another game. Pick: Ohio State -39.5 — Tom Fornelli
No. 11 USC at No. 18 Michigan
3:30 pm | CBS, Paramount+ with ShowtimeCBSSports.com, CBS Sports App — Michigan is turning to freshman Alex Orji in hopes of sparking the offense after a rough start. But it’s clear that the Michigan staff doesn’t trust Orji to throw the football, which means the Wolverines will still be one-sided. The Trojans look very strong defensively under first-year coordinator D’Anton Lynn and should have the luxury of contributing against the run. USC also has enough firepower to exploit soft spots in a Michigan defense that isn’t as strong as its 2023 counterpart. Select: USC -5.5 — David Cobb
No. 12 Utah in the No. 14 Oklahoma State
4 p.m Fox, chest (Try it for free) — The Utes are ranked atop the Big 12 for a reason, and now they get a chance to flex their muscles with a trip to Stillwater. Oklahoma State showed real weakness on defense and against mobile quarterbacks, creating opportunities for the Rising to attack the lungs. If Ollie Gordon II can’t get on the road, the Utes have a strong road to victory. Pick: Utah +130 –Shehan Jeyarajah
No. 6 Tennessee at No. 15 Oklahoma
7:30 pm | ABC, chest (Try it for free) — There are some concerns about this being an away game for Tennessee; The Volunteers haven’t been great in big games on the road under Josh Heupel, and this will be Nico Iamaleava’s first start in a hostile environment. But this seems like a perfect match for Tennessee. Oklahoma’s offensive line has never been better. The Vols have one of the best defenses in the country. Oklahoma struggles to keep putting points on the board. Tennessee scored just twice. Both defenses are very good, so this one may be a little sloppy early on, but Tennessee’s offense will hit enough plays to get out of Norman with success. Pick: Tennessee -7 — Come Backus
Which college football picks can you confidently pick in Week 4? Visit SportsLine to see which teams will win and broadcast coverage — all from a proven computer model that has returned more than $2,000 in profits since its inception — and find out.
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